Program

The Catalyst: This session will showcase the latest advancements in enzyme technology, focusing on the exploration and optimization of enzymes as key catalysts in biocatalytic processes.

The Reaction: These talks will delve into the specific chemical reactions catalyzed by enzymes, highlighting how optimized reaction conditions can lead to maximum efficiency.

The Process: Join this session to discuss the development of scalable and sustainable processes, bridging the gap from basic research to industrial application.

Application: Learn about the practical applications of biocatalytic processes across various industries and explore innovative approaches to expanding their potential.

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Day 1: Monday, 31.03.2025 THE CATALYST
10:00 AM	Registration
10:30 AM	Sarah A. Berger, Christopher Grimm, Isabel Oroz-Guinea, Stephan Vrabl, Marisa Sánchez Quinteros, Marco Cespugli, Andreas Krassnigg, Tobias Schopper, Irene Marzuoli, Bettina M. Nestl, Georg Steinkellner, Christian C. Gruber, Hans Iding, Kurt Puentener, Francis Gosselin, Serena Bisagni, Wolfgang Kroutil, Joerg H. Schrittwieser (University of Graz, Austria) “Systematic profiling of IRED and RedAm substrate scope in direct and indirect reductive amination” (Invited Talk)
11:30 AM	Ewald P.J. Jongkind, Jack Domenech, Arthur Govers, Marcel van den Broek, Jean-Marc Daran, Gideon Grogan and Caroline E. Paul (Delft University of Technology, The Netherlands) “Discovery and synthetic applications of a NAD(P)H-dependent reductive aminase from Rhodococcuserythropolis”
12:00 PM	Anya Miletic, Ashleigh Burke, Thomas Thorpe, Sarah Montgomery, Beatriz Dominguez, Anthony Green, and Nicholas Turner (University of Manchester, UK) “Engineering of a Multifunctional Imine Reductase”
12:30 PM	Lunch incl. company exhibition
02:00 PM	Gerrit Poelarends, Laura Bothof, Xiaofang Gong, Peter Fodran (University of Groningen, The Netherlands) “Engineering C-N lyasesfor stereoselective synthesis of tertiary amines”
02:30 PM	Claudia Binda, Lorenzo Basile, Chiara Poli, Lars L. Santema, Răzvan C. Lesenciuc, Marco W. Fraaije (University of Pavia, Italy) “Discovery of a thermostable bacterial monoamine oxidase”
03:00 PM	Josemarco Mendoza-Avila, Volker Döring, Madeleine Bouzon, Ivan Dubois, Tanja Knaus, Louis M. M. Mouterde, Anne Zaparucha, Francesco G. Mutti, and Carine Vergne-Vaxelaire (Université Paris-Saclay, France) “Biotransformations with E. colifor amine synthesis: a whole-organism approach beyond enzymes”
03:30 PM – 04:30 PM	Speedtalks
04:30 PM – 07:00 PM	Poster-Session + Welcome reception
From 07:00 PM	Pub tour / Domkeller (optional)

Day 2: Tuesday, 01.04.2025 THE REACTION
09:00 AM	Kenichi Matsuda (Hokkaido University, Japan) “Bacterial Hydrazine Biosynthetic Pathways Featuring Cupin/Methionyl tRNA Synthetase-like Enzymes” (Invited Talk)
10:00 AM	Simon Schröder, Yongxin Li, Nikita Pal, Lindelo Mguni, Bastian Daniel, Karl Gruber, Artur Maier, Dirk Tischler, Martin A. Hayes and Sandy Schmidt (University of Groningen, The Netherlands) “Novel Piperazate Synthases As Versatile Biocatalysts Forming Nitrogen-Nitrogen Bonds”
10:30 AM	Coffee break

Day 2: Tuesday, 01.04.2025 THE PROCESS & APPLICATION
11:00 AM	I. Benítez-Mateos, D. Lim, V. Marchini, D. Roura Padrosa, H. Wu, F. Buono, F. Paradisi (University of Bern, Switzerland) “Implementation of enzymes in amine-focussed processes” (Invited Talk)
12:00 PM	Andreas Bommarius, Adam Caparco, Robert Franklin and David Witdorchica (School of Chemical & Biomolecular Engineering, USA) “Novel properties of engineered amine dehydrogenases”
12:30 PM	Lunch incl. company exhibition
01:45 PM	Tandem Talk: Berit Rothkranz, William von Westarp, Doris Hahn, Nina Klos, Laura Grabowski and Dörte Rother (Forschungszentrum Jülich and RWTH Aachen University, Germany) “The enzymatic metaraminol synthesis – when the cofactor is irreversibly complexed with the product”
02:30 PM	Sven Tiedemann, Jan Eric Neuburger, Alina Gazizova, Tom Kunde, Simon Last, Kevin Klust, Annabell Stang and Jan von Langermann (Otto-von-Guericke University Magdeburg, Germany) “Preparative Synthesis of Chiral Amines and Amino Acids Using in-situ Product Crystallization Strategies”
03:30 PM – 06:00 PM	City tour
From 07:00 PM	Conference Dinner

Day 3: Wednesday, 02.04.2025 THE PROCESS & APPLICATION
09:00 AM	Thomas Ruch (Novartis, Switzerland) (Invited Talk)
10:00 AM	Stefania Patti, Ilaria Magrini Alunno, Riccardo Semproli, Fabio Sangalli, Davide Tessaro, Daniela Monti, Sergio Riva, Daniela Ubiali and Erica Elisa Ferrandi (University of Milan, Italy) “Efficient Two-Step Synthesis of Nor(pseudo)ephedrines Using Immobilized Biocatalysts”
10:30 AM	Coffee break
11:00 AM	Donato Calabrese, Niels Borlinghaus, Bettina Nestl and Lars Lauterbach (RWTH Aachen University, Germany) “Rocket fuel on a budget: Development of a biocatalytic approach for H₂-driven reductive hydrazination using IRED and a [NiFe]-hydrogenase”
11:30 AM	Katharina Neufeld (Johnson & Johnson, Belgium)
12:00 PM Closing & Departure

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